New technology changes society. It offers innovative opportunities that challenge existing socio-economic systems. Neo Manufacturing proposes that new technologies can bring the youth and sustainable work back into the city. Rather than the logic that seeks to replace human work with machines, Neo Manufacturing envisions machines working with humans to create new modes of production and consumption. Scientists, engineers, artists, designers, and architects working in the field of artificial intelligence, robotics, 3D printing, and digital fabrication will be invited to explore hybrid approaches that can thrive in the inner city.